quarta-feira, 10 de abril de 2013

Cardiff University dean of medicine cleared of research misconduct


Professor Paul Morgan and other members of his research group were cleared by a formal investigation panel.
But four allegations of image manipulation in articles were upheld against a former staff member.
Prof Morgan, who researches diseases, said the actions of one individual had a "profound effect" on his reputation.
A clinical academic, the professor heads a team which Cardiff University's website said is "internationally recognised for its expertise and contribution to the field of complement biology".
He remained in his post during the investigation by the panel, which was chaired by a former Cardiff circuit judge.
"Throughout this episode, I have maintained my innocence, and that of my research team, in the face of allegations of research misconduct," he said.
"I am pleased that the independent panel has rejected all allegations against me and concluded that there was no case to answer.

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The episode has been extremely upsetting - not only for me personally, but also for friends, family, colleagues - and particularly, my research team”
Prof Paul Morgan
"The episode has been extremely upsetting, not only for me personally, but also for friends, family, colleagues - and particularly, my research team."
Prof Morgan said he believed the allegations needed investigation "to ensure the highest academic standards are maintained".
"The university has examined more than 40 published articles in relation to my research group and no additional findings of academic misconduct were made.
"However it is a matter of deep regret that the actions of one individual has had such a profound effect on the academic reputations of my colleagues and myself."
He added that after eight difficult months he was now looking on focusing his energies on undertaking research that will help with the treatment of human diseases.
The inquiry rejected all allegations against Prof Morgan and members of his research team, but upheld four allegations of misconduct against the former university employee.
The panel also said that Prof Morgan - the co-author of the four articles in question - would not have been aware that the individual had included manipulated images in the articles.
Cardiff University said it took allegations of academic research misconduct against staff extremely seriously.
"The panel did find that allegations of data manipulation against a former member of university staff were substantiated and recommends that protocols are put in place to ensure that data and original image files are in future viewed and assessed prior to submission for publication," a spokesperson said.
"Cardiff University accepts these findings and recommendations and will now take action to put in place procedures to ensure that incidents of this sort do not recur."

terça-feira, 9 de abril de 2013

Obamacare made medicine dangerous to your health


Safety is always cited as a reason to involve government in medicine. But those of us on the front lines, those of us actually seeing patients, realize that government cannot insure your safety – and generally makes things worse.

Recently we and every other hospital and clinic which accepts Medicare payment has implemented electronic medical records. Electronic medical records were forced on us as part of Medicare and Obamacare, purportedly to help avoid redundancy of testing, to make past medical history more available and to make it easier to monitor the disease processes both individually and in aggregate.


Trust me, it does none of these things, but it does make you, the patient, at more risk of gross medical error.

I don’t know any non-university physician who likes electronic medical records. The issues I raise should not be seen as isolated to my facility, nor to my particular brand of EMR (electronic medical records).

In a busy orthopaedic clinic, in order to see patients efficiently, records may be dictated after the patient has left. It is not uncommon to make an error in recording the location of an injury or lesion, mistaking left for right either through dictation error, thinking backwards or transcription error. For example, I see a patient with a broken arm, and accidentally dictate right when it is the left arm that is broken. Thankfully, there are multiple layers of checks and balances to catch such mistakes. With a paper chart, this can easily be corrected on the note so that there is no evidence of the wrong side being recorded – we simply retype the note. Or the error can be crossed out, so the error is still visible, but clearly has been corrected.


Not so with EMR. Once the note is signed off for 24 hours, it cannot be changed. The best that can be done (at least in some systems) is that an addendum can be put in the chart. This little correcting note, for example, “Regarding Mrs. Jones wrist fracture, the injury occurred on the left, not the right as previously noted,” may or may not be stored next to the note with the error. It may or may not be obvious to anyone needing information about the patient. In other words, a physician seeing the patient in the future who is not familiar with the case may read the note, but not the addendum, because he does not know to look for it. It is obvious to any physician, but apparently not to the people who write these programs, that this is a major safety hazard.

The risk of medical error is compounded by the new digital X-ray systems. For decades, ever since X-rays have been used in operating rooms, there has been an industry standard. The X-ray was put up on the view box with left on left, and right on right. As a resident, it was my job to insure that the X-rays were correctly hung. So if I am operating on a left sided lumbar disc, the X-ray picture on the wall mirrors the reality with the ruptured disc on the left.

But in the new digital world, the industry standard is left on right. In other words, in the operating room the new standard for displaying images is backwards from historical precedent and from reality. Now, with a brain lesion, kidney mass, ruptured disc, or fracture on the left, the digital X-ray shows it to the right of the screen.


This came about because radiologists, not surgeons, developed the systems for digital X-ray, and their standard is to view the patient from the feet up, i.e. bottom to top, so the patient’s right is on the radiologist’s left. But the purpose of X-rays is not for radiologists to read them and get paid, but rather for surgeons and other physicians to use the X-rays for patient care.

I love my radiologist friends, but to adopt the radiologists’ standard over the operating surgeons’ is nightmarish. It is like setting airplane controls, not for the pilot, but to the standard of the repair crews. And although the young surgeons growing up with this may adapt to some degree, for those of us with over 20 years in the operating room, it is one more reason to retire early. Backwards X-rays add one more more level of uncertainty to an already complex situation.

Lets put this all together. Suppose there is a patient – a non verbal elderly man who is being taken to the operating room to have a right-sided brain tumor removed. In clinic the note was recorded in EMR erroneously by the resident physician as a left sided lesion. He recognized the error later and typed an addendum. But in the new world of medicine, where doctors are shift workers, he is not the one who prepares the patient for surgery. The next resident prepares the operative consent and paperwork for surgery, and he doesn’t find the addendum. So, he schedules the patient for a left-sided tumor removal. The patient – who cannot speak – cannot confirm verbally to the preoperative nurse that the procedure is on the right, a final check in most patients. And the surgeon, in the OR, who is used to having X-rays reflect the lesion as it really is in respect to left and right, sees the MRI of the tumor on the left of the screen, reads the notes and proceeds to explore the left side of the brain. Unfortunately, the tumor is on the right.

This happened very rarely in the old system. But, I expect an increase in frequency. Imagine if suddenly the auto industry changed the standard for steering wheels and now, when you turn the wheel to the right the car goes left. You may be OK most of the time, but when you are tired, anxious or just have a momentary lapse – boom. You revert to the old habits. It is human nature.

I would love to say that physicians are perfect, but we are human. As private individuals, physicians developed a system of medical practice over years that worked to prevent such errors, and overnight, the federal government replaced it with a top-down experimental system that has never been used or even tried.

Safety is everyone’s concern, but can only be practiced by those actually doing the patient care. And no one has more interest in your safety than your doctor. Instead of helping us, government mandates have made it harder and harder to be safe. In my hospital recently, an incident report was made after a patient did get to the Operating Room with a history that recorded the problem on the wrong side. Fortunately the correct operation was done.

More tragically, in Massachusetts, a patient received a kidney transplant from a patient who was Hepatitis C positive. Six physicians reviewed the donor’s chart and missed the fact that the donor was positive for the virus. In doing a so called “root cause analysis,” you have to either believe that six well-trained, seasoned specialists suddenly became carelessly incompetent, that the information was not readily available or that the information was presented in an unusable format. Although the uninitiated may think EMR makes everything readily available, the opposite is true. Electronic records present data in an impossible laundry list with no prioritizing and poor labeling.

We as an industry are an accident waiting to happen, in spite of pleas from physicians. It is no coincidence that the world-famous Barrows Neurologic Institute was one of the last hospitals to adopt an electronic X-ray system, or that surgical specialists have drug their feet on EMR in general.

Before I undergo any surgery on my own body, I will make sure to write “no” on the uninvolved side, and I carry a one-page medical summary of my diagnoses and medications wherever I go. With the government smart guys in charge, it is more critical than ever for patients to take an active role in safeguarding their own health.



segunda-feira, 8 de abril de 2013

New Study Identifies Better Solution for Itch


Shoppers spend more than $352 million annually on anti-itch remedies and they are faced with a wealth of options of over-the-counter products on store shelves.  A new study published in the international peer-reviewed journal, Acta Dermato-Venereologica, may just help itch sufferers zero in on the most effective remedies.Researchers at the Wake Forest School of Medicine compared a topical hydrogel containing aluminum acetate and strontium (sold commercially as TriCalm Hydrogel) head-to-head against two products commonly marketed for anti-itch; hydrocortisone and diphenhydramine (Benadryl 1%).  TriCalm was "significantly superior" to the other two over-the-counter anti-itch agents reducing both the peak intensity and duration of the subjects' itch, according to the results of the study.

"Managing itch, especially chronic itch, is challenging," said Gil Yosipovitch, MD, of the Dermatology Department at Wake Forest University and one of the study's authors. "Many of the typical over-the-counter remedies are not effective and what this study tells us is that TriCalm products are likely a more effective solution than other over-the-counter options."

The double blinded, vehicle-controlled study was looking specifically at non-histamine induced itches.  The researchers induced itch in the subjects using a tropical plant called cowhage typically used when studying non-histamine-induced itch, This type of itch is more related to chronic itch, where antihistamines do not have any anti-itch effect.

New TriCalm Hydrogel is steroid-free and is now available at Walgreens, CVS and other retailers.
TriCalm is a product of Cosmederm Bioscience, a specialty pharmaceutical company focused on dermatology and pain management. Drawing on years of laboratory research and published clinical work, Cosmederm develops products that target a wide variety of skin diseases and inflammatory conditions. With its portfolio of patented analgesic and anti-inflammatory compounds, Cosmederm has developed uniquely effective topical products ranging from cosmeceuticals and OTC drugs to a pipeline of prescription drug candidates. Cosmederm is the sole owner of COSMEDERM-7, a patented compound made from strontium that has been developed for dermatological applications. Cosmederm's product lines include TriCalm™, REFINITY™ Skin Solutions, and COSMEDERM SKIN SCIENCE™.

sexta-feira, 5 de abril de 2013

Experts gather for national melanoma summit


New Zealand and international experts in melanoma are gathering in Wellington on Friday 5 April to hear about recent developments, identify priorities for action and work more closely to reduce melanoma's incidence and impact.

New Zealand has one of the highest rates of melanoma skin cancer in the world, and over 300 people here die of melanoma each year. It is the most commonly registered cancer in men aged 25-44 and the second most commonly registered cancer in women aged 25-44.

Exposure to ultraviolet radiation (UV) from the sun is the primary cause of most melanomas and the risk of developing melanoma is strongly related to a history of one or more sunburns in childhood or adolescence.

Speakers include a number of New Zealanders based both here and overseas who are recognised internationally for their melanoma expertise. They include:
•    Professor David Elder, Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania. Professor Elder was recently involved in the development of international guidelines for lesion classification. Professor Elder's attendance is sponsored by the Genesis Oncology Trust.
•    Professor John Hawk, Emeritus Professor of Dermatology at St Thomas Hospital London and President, European Society for Photo Dermatology. Professor Hawk will address current trends in incidence and strategies for prevention of malignant melanoma. Professor Hawk's attendance is sponsored by the Cancer Society of New Zealand.
•    Dr Amanda Oakley, President of the New Zealand Dermatological Society and a specialist dermatologist based in Hamilton. Dr Oakley created and manages DermNet NZ, a vast online dermatological resource that receives more than one million visitors a month.
•    Dr Mary-Jane Sneyd, medical epidemiologist and Senior Research Fellow at the Department of Preventive and Social Medicine, University of Otago, Dunedin. Dr Sneyd has recently developed a New Zealand-specific prediction model to estimate an individual's risk of developing melanoma.  Dr Sneyd's attendance is sponsored by the Melanoma Foundation of New Zealand.
Melanoma Summit New Zealand 2013 is hosted by MelNet with support from the Health Promotion Agency, Cancer Society of New Zealand and Melanoma Foundation of New Zealand.
Further information:
The media is welcome to attend the summit. The keynote speakers are happy to be interviewed during the summit.  Please contact:
•    Jane Thompson on 021 883491, jane@cmq.co.nz beforehand to arrange an interview time, or
•    Lynne St.Clair-Chapman, Cancer Society National Communications Manager, on 5 April, the day of the summit, on 027 444 4150, lynne@cancer.org.nz.

Sponsors of the Melanoma Summit are: Roche Products, Cancer Society of New Zealand, Genesis Oncology Trust, Path Lab, Melanoma Foundation of New Zealand, Bristol-Myers Squibb, Abbott Molecular and New Zealand Dermatological Society.

More information about the Summit is available here: http://www.melanoma.org.nz/MelNet/News/Melanoma-Summit-2013/

quinta-feira, 4 de abril de 2013

Medicine by Text Message: Learning From the Third World


In the last decade, community health efforts have been made more effective by a simple insight: that time, money, and sometimes even lives can be saved through texting. At St. Gabriel's Hospital in Malawi, for example, 75 community health workers were trained to use text messages to communicate patient information, appointment reminders, and other health-related notifications to patients. Through this mobile health, or mHealth, initiative, the hospital saved approximately 2,048 hours of worker time and $3,000 in fuel, while doubling the capacity of the tuberculosis treatment program.

The case for this growing field in the developing world provokes some controversy, however. Tina Rosenberg, writing in The New York Times, argued recently that the field is in flux. "Roughly a decade after the start of mHealth ... these expectations are far from being met," she writes. "The delivery system is there. But we don't yet know what to deliver." Most of the testing done in the field, she goes on to argue, has focused on feasibility, not real health impacts. What's needed, many insist, is the use of randomized control trials -- the gold standard in science -- to help determine what actually helps the world's poor, versus what development workers and funders assume will.

After about a decade of attracting big philanthropic investment without enough measurable results, Uganda and South Africa have both put a hold on any new mHealth pilots in their countries. And as the developing world closes its doors, some nonprofits are turning their sights to the U.S. for further study. "While there is still much to do in low and middle income countries, there is a lot that can be learned and transferred from the experience of designing and implementing mHealth systems in resource constrained settings here in the U.S.," explained Patricia Mechael, the executive director of mHealth Alliance at the United Nations Foundation. If they can improve health outcomes through randomized control trials, they may be able to renew the philanthropic sectors' belief in the viability of the field.

And the U.S. could profit as well. Mobile interventions in prenatal care and chronic diseases, like diabetes, have already proven particularly successful, in large part because they are an easy way for people to take charge of their own health. Price Waterhouse Cooper estimates that mHealth interventions in the U.S. could save $10,000 per diabetic patient per year. The U.S. current spends $218 billion on diabetes every year.

Text messages have a wildly high "open and read" rate -- 97 percent versus 5 to 20 percent for email. What began as a field that mostly tackled approaches to improving care for HIV and AIDS patients has expanded its scope widely in the last few years. In 2011, a Lancet study reported that text messages to remind health workers in Kenya about the proper guidelines for malaria management improved care by 23.7 percent immediately after intervention and continuing to 24.5 percent six months later. One recent project even attempted to reduce depression among teenagers in Auckland, New Zealand using a cognitive behavioral therapy approach gone mobile; over three-quarters of participants viewed at least half of the uplifting text messages sent to them and 66.7 percent said it helped them in getting rid of negative thoughts.

Medic Mobile, a non-profit organization founded in 2009, has used technology -- like text messaging immunization reminders or providing apps with basic, life-saving information about prenatal care -- in over 20 countries on a wide variety of projects. Their efforts, thus far, have reached 3,500,000 people, or 700,000 households. This month and next, it will launch two U.S.-based initiatives.

One program, which will begin on April 18, aims to use text message reminders to increase appointment attendance among the largely immigrant, Latino population served by the San Mateo Medical Center. Those who opt-in will be able to confirm and reschedule appointments via text message. "These kinds of clinics currently have full-time staff devoted to calling and trying to track down patients," explained Josh Nesbit, the organization's CEO and co-founder. "We're trying to harness the power of asynchronicity to interact with as many people as possible in an efficient way."

The other project, launched on March 18, provides low-income, uninsured families with customized tracking and management software created in partnership with the Lucille Packard Children's Hospital at Stanford. The platform includes a reminder system for type I diabetic children and their caretakers, which can receive and recognize various types of SMS "check-ins" for blood sugar levels and respond appropriately to high or low values. Parts of it are structured like a game, where patients receive points as incentive for taking a proactive role in their care.

In addition to gaining the data they need to return to the developing world, the group is hoping to bring some of what they've learned over the last four years in the developing world to bear on these U.S.-focused projects -- global health experts are calling this increasingly common development "south to north" learning. Mechael explained, "Much of our work is focused on the enabling environment for mHealth in low and middle income countries, and frequently I find myself giving talks in the U.S. about what America can learn about mHealth from Africa, Asia, and Latin America."

As Medic Mobile embarks on the San Mateo Project, the tricky system was in the private, not public sector. They quickly learned that navigating monsoons in Bangladesh was a cake walk compared to navigating the deluge of bureaucracy to be found in an American health clinic. "It took us six months to just integrate our approach with their electronic filing system," said Nesbit. "That's really daunting to think about on a per project basis, so part of the work ahead is to figure out how to create mobile tools that aren't threatening to the electronic medical record providers, so we can just hand this off to clinics and they can do it on their own."

Nesbit predicts that text messaging is just one of many "south to north" learnings that will change the way health care is structured in the U.S. in the coming years; he also believes that the community health worker model, which revolutionized the quality of care in places like Rwanda and Ethiopia, will become increasingly common stateside.

To date, Medic Mobile has affected one million people's lives in Malawi, where the majority of people live off of less than $2 a day. Could the same kind of impact be possible in the U.S. context? This is part of what they are out to learn in the coming months. The results could have far-reaching consequences for the kinds of technological tools that we bring to bear on the U.S. health care crisis in the years ahead.

quarta-feira, 3 de abril de 2013

Matters of milk and medicine


Milk might not be all that we have been brought up to believe, claims author and naturopath N. K. Sharma

Breaking away from a common notion is not an easy task. With Milk: A Silent Killer Dr. N. K. Sharma wants the world to know that a glass of milk could turn into a nightmare for you and your loved ones.

Conventional wisdom, passed down over generations, holds that milk is good for health, and the slightly more suspicious claim that it will ensure good scores on the report card.

It is a source of calcium but could also be the reason for cancer. Sharma, a well known naturopath, has come up with a revised version of his book Milk, which was published in 1987. “Since my childhood I have been a lover of milk and been a sufferer too. I used to do medicines and yoga and never doubted why my ailing condition was not being cured,” he says.

A large intake of milk over several years can lead to cancer, as the magnesium it contains can get slowly deposited in the body.

The doctor also believes that prevention is better than cure and boasts proudly about he has shielded his family from any form of disease. “God has graced us with a healthy mind and body, nobody is born ill. It is we who deplete the condition of our body through our ignorance,” he says.“Disease is not natural, health is natural state of body; medicines should not become a lifestyle and it should be treated as a medicine only.”

But to shatter the common myth that has been here for ages is not an easy task. “We have to become the message. We know what is the right thing to do, we will certainly benefit from it later. We have been brought up to believe milk is good, it is high time for it to change,” he signs off.

segunda-feira, 1 de abril de 2013

Sunderland salon offers teenagers skin treatment in bid to curb suicide-linked acne drug

Teenagers with acne are being offered half-price 'blue-light' treatment at Pure Bliss on Sea Road in Fulwell. Teenagers with acne are being offered half-price 'blue-light' treatment at Pure Bliss on Sea Road in Fulwell.
A BEAUTY salon is offering alternative skin treatments in a bid to prevent teens taking a controversial drug.
Pure Bliss, Fulwell, is trialling a clear skin course to highlight the use of light therapy which can help cure acne.
Salon owner Lisa Watson said she wants parents and their children to know there are other treatments available before they take Roaccutane, which has been linked to depression, leading to suicide.
“I watched a programme a couple of months ago about the drug and was shocked to see that it has been linked to depression and young people committing suicide,” she said.
“It is available on prescription from a dermatologist and is only supposed to be given for the most severe cases of acne, but one of the people on the programme only had spots on his back and he was given it.
“We use Omnilux light therapy in the salon, and I wanted to start offering it half price to teens with severe acne to show that there are other treatments out there, and to make it accessible to them.”
The clear skin course uses a special blue light, which penetrates into the skin to stop the spread of the bacteria that causes acne.
A red light is also used to reduce inflammation of the skin and assist in its healing process.
“We do two sessions of the blue light, then one of the red, and repeat that,” said Lisa. “We’ll also offer other treatments – such as micro-dermabrasion – if the therapists think that is required.
“I don’t want to go against any doctors, I just want to let people know about alternative therapies.”
The course of eight treatments will be offered to teenagers with a severe case of acne for £145. The salon also gives skin care advice to stop acne.

Source: http://www.sunderlandecho.com/news/business/latest-news/sunderland-salon-offers-teenagers-skin-treatment-in-bid-to-curb-suicide-linked-acne-drug-1-5537771